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1

Synthesis and Antiviral Activity of Lupane Triterpenoids and Their Derivatives

O. B. Flekhter, E. I. Boreko, L. R. Nigmatullina, N. I. Pavlova, N. I. Medvedeva, S. N. Nikolaeva, O. A. Ashavina, O. V. Savinova, L. A. Baltina, F. Z. Galin, G. A. Tolstikov

Journal:

Pharmaceutical Chemistry Journal

Year:

2004

Language:

english

File:

PDF, 85 KB

english, 2004

2

Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses

N.I. Pavlova, O.V. Savinova, S.N. Nikolaeva, E.I. Boreko, O.B. Flekhter

Journal:

Year:

2003

Language:

english

File:

PDF, 54 KB

english, 2003

3

Synthesis of 1,2,3-Thiadiazolo Terpenoids on the Basis of Cyclopentanonopimaric and Betulonic Acids.

O. B. Flekhter, E. V. Tret'yakova, N. I. Medvedeva, L. A. Baltinax, F. Z. Galin, G. A. Tolstikov, V. A. Bakulev

Journal:

Year:

2004

File:

PDF, 138 KB

2004

4

Synthesis and hepatoprotector activity of 2-arylidene methylbetulonate derivatives

O. B. Flekhter, L. T. Karachurina, L. R. Nigmatullina, L. A. Baltina, F. S. Zarudii, V. A. Davydova, L. V. Spirikhin, I. P. Baikova, F. Z. Galin, G. A. Tolstikov

Journal:

Pharmaceutical Chemistry Journal

Year:

2000

Language:

english

File:

PDF, 268 KB

english, 2000

5

Synthesis of Methyl [3,2-c]-Pyrazol-lup-20(29)-en-28-oate

L. R. Nigmatullina, O. B. Flekhter, L. A. Baltina, N. I. Medvedeva, G. A. Tolstikov

Journal:

Chemistry of Natural Compounds

Year:

2002

Language:

english

File:

PDF, 17 KB

english, 2002

6

ChemInform Abstract: Isomerization of Glycyrrhizinic Acid. Antiulcer Activity.

L. A. BALTINA, N. G. SERDYUK, O. B. FLEKHTER, L. V. KRASNOVA, V. A. DAVYDOVA, A. F. ISMAGILOVA, F. S. ZARUDII, G. A. TOLSTIKOV

Journal:

Year:

1997

File:

PDF, 29 KB

1997

7

ChemInform Abstract: Stereoselective Synthesis of 2-Deoxy-α-D-arabino-hexopyranosides of Triterpenic Alcohols.

L. A. BALTINA, O. B. FLEKHTER, E. V. VASIL'EVA, G. A. TOLSTIKOV

Journal:

Year:

1997

File:

PDF, 30 KB

1997

8

ChemInform Abstract: Stereoselective Synthesis of 2,6-Dideoxy-α-L- arabinohexopyranoside of Glycyrrhetic Acid (V) in the Presence of Iodine-Containing Promotors.

O. B. FLEKHTER, L. A. BALTINA, E. V. VASIL'EVA, G. A. TOLSTIKOV

Journal:

Year:

1997

File:

PDF, 34 KB

1997

9

ChemInform Abstract: Simplified Stereoselective Synthesis of Triterpene 3-O-2-Deoxy-α- D-glycosides.

O. B. FLEKHTER, L. A. BALTINA, E. V. VASILJIEVA, G. A. TOLSTIKOV

Journal:

Year:

1997

File:

PDF, 32 KB

1997

10

ChemInform Abstract: Stereoselective Synthesis of Triterpene and Steroid 2-Deoxy-α- glycosides Using Iodonium Dicollidine Perchlorate.

L. A. BALTINA, O. B. FLEKHTER, E. V. VASIL'EVA, G. A. TOLSTIKOV

Journal:

Year:

1997

File:

PDF, 37 KB

1997

11

ChemInform Abstract: Stereoselective Synthesis of Triterpene 2-Deoxy-α-D-lyxo- hexopyranosides.

L. A. BALTINA, O. B. FLEKHTER, E. V. VASIL'EVA, G. A. TOLSTIKOV

Journal:

Year:

1997

File:

PDF, 33 KB

1997

12

ChemInform Abstract: Direct Stereoselective Synthesis of Triterpene and Steroid 2-Deoxy-. alpha.-glycosides.

O. B. FLEKHTER, L. A. BALTINA, G. A. TOLSTIKOV

Journal:

Year:

1997

File:

PDF, 32 KB

1997

13

ChemInform Abstract: Glycosylation of Betulin Acetates with Glycals.

O. B. FLEKHTER, L. A. BALTINA, L. V. SPIRIKHIN, I. P. BAIKOVA, G. A. TOLSTIKOV

Journal:

Year:

1998

File:

PDF, 32 KB

1998

14

ChemInform Abstract: Synthesis and Hepato-Protective Activity of 2-Arylidene Derivatives of Methyl Betulonate.

O. B. Flekhter, L. T. Karachurina, L. R. Nigmatullina, L. A. Baltina, F. S. Zarydii, V. A. Davydova, L. V. Spirikhin, I. P. Baikova, F. Z. Galin, G. A. Tolstikov

Journal:

Year:

2000

File:

PDF, 27 KB

2000

15

ChemInform Abstract: Synthesis, Antiinflammatory, and Antiulcer Activity of Some 2-Substituted Derivatives of Betulonic Acid, Methyl Betulonate and Lupenone.

O. B. Flekhter, L. R. Nigmatullina, L. T. Karachurina, L. A. Baltina, F. S. Zarudii, V. A. Davydova, F. Z. Galin, G. A. Tolstikov

Journal:

Year:

2001

File:

PDF, 30 KB

2001

16

ChemInform Abstract: Approach to the Synthesis of Glycyrrhizinic Acid from Glycyrrham. Pharmacological Properties.

L. A. Baltina, R. M. Kondratenko, S. R. Mustafina, O. B. Flekhter, Yu. I. Murinov, V. A. Davydova, F. S. Zarudii, A. F. Ismagilova, G. A. Tolstikov

Journal:

Year:

2001

File:

PDF, 23 KB

2001

17

Synthesis of 3-O-Acetylbetulinic and Betulonic Aldehydes by Swern Oxidation and Pharmacological Activity of Their Oximes.

O. B. Flekhter, O. Yu. Ashavina, E. I. Boreko, L. T. Karachurina, N. I. Pavlova, N. N. Kabal'nova, O. V. Savinova, F. Z. Galin, S. N. Nikolaeva, F. S. Zarudii, et al. et al.

Journal:

Year:

2002

File:

PDF, 34 KB

2002

18

Synthesis and Antiinflammatory Activity of New Acyl Derivatives of Betulin

O. B. Flekhter, N. I. Medvedeva, L. T. Karachurina, L. A. Baltina, F. S. Zarudii, F. Z. Galin, G. A. Tolstikov

Journal:

Year:

2003

File:

PDF, 111 KB

2003

19

Preparation of Betulinic Acids from Betulin Extract. Antiviral and Antiulcer Activity of Some Related Terpenoids.

O. B. Flekhter, L. R. Nigmatullina, L. A. Baltina, L. T. Karachurina, F. Z. Galin, F. S. Zarudii, G. A. Tolstikov, E. I. Boreko, N. I. Pavlova, S. N. Nikolaeva, et al. et al.

Journal:

Year:

2003

File:

PDF, 88 KB

2003

20

Antiinflammatory Activity of Quinopimaric Acids and Synthesis of Amides of These Acids.

O. B. Flekhter, E. V. Tret'yakova, F. Z. Galin, L. T. Karachurina, L. V. Spirikhin, F. S. Zarudii, G. A. Tolstikov

Journal:

Year:

2003

File:

PDF, 73 KB

2003

21

Synthesis and Antiulcer Activity of Quinopimaric Acid Derivatives.

O. B. Flekhter, E. V. Tret'yakova, N. S. Makara, S. F. Gabdrakhmanova, N. Zh. Baschenko, F. Z. Galin, F. S. Zarudii, G. A. Tolstikov

Journal:

Year:

2003

File:

PDF, 116 KB

2003

22

Lupane Triterpenes and Derivatives with Antiviral Activity

L. A. Baltina, O. B. Flekhter, L. R. Nigmatullina, E. I. Boreko, N. I. Pavlova, S. N. Nikolaeva, O. V. Savinova, G. A. Tolstikov

Journal:

Year:

2004

File:

PDF, 92 KB

2004

23

Synthesis of 2-Amino-4-aryl-3-cyano-4H-pyrano and 2-Amino-3-cyanothieno Derivatives of Cyclopentanonopimaric Acid

E. V. Tret'yakova, O. B. Flekhter, F. Z. Galin, L. V. Spirikhin, G. A. Tolstikov

Journal:

Year:

2004

File:

PDF, 106 KB

2004

24

Synthesis of 1,6-Dihydro- and 4-(4-Nitrophenyl)-1,2,3,4-tetrahydropyrimidine, 1H- and 1-Phenyl-1H-pyrazole, and Isoxazole Derivatives on the Basis of Cyclopentanonopimaric Acid.

E. V. Tret'yakova, O. B. Flekhter, F. Z. Galin, L. V. Spirikhin, I. P. Baikova, G. A. Tolstikov

Journal:

Year:

2004

File:

PDF, 151 KB

2004

25

Synthesis and Pharmacological Activity of Acylated Oximes of Betulonic Acid and 28-Oxo-allobetulone.

O. B. Flekhter, E. I. Boreko, L. R. Nigmatullina, N. I. Pavlova, N. I. Medvedeva, S. N. Nikolaeva, E. V. Tret'yakova, O. V. Savinova, L. A. Baltina, L. T. Karachurina, et al. et al.

Journal:

Year:

2004

File:

PDF, 77 KB

2004

26

Synthesis and Antiviral Activity of Lupane Triterpenoid Derivatives.

O. B. Flekhter, E. I. Boreko, L. R. Nigmatullina, N. I. Pavlova, N. I. Medvedeva, S. N. Nikolaeva, O. A. Ashavina, O. V. Savinova, L. A. Baltina, F. Z. Galin, et al. et al.

Journal:

Year:

2004

File:

PDF, 22 KB

2004

27

Oxidation of Betulin and Its Acetates with Dimethyldioxirane.

Olga Yu. Ashavina, Nataliya N. Kabalnova, Oxana B. Flekhter, Leonid V. Spirikhin, Fanur Z. Galin, Lidiya A. Baltina, Zoya A. Starikova, Mikhail Yu. Antipin, Genrikh A. Tolstikov

Journal:

Year:

2005

File:

PDF, 36 KB

2005

28

Synthetic Transformations of Higher Terpenoids. Part 11. Synthesis of A-Nor-5βH-19β,28-epoxy-18α-olean-3-one Derivatives.

N. I. Medvedeva, O. B. Flekhter, E. V. Tretyakova, F. Z. Galin, L. A. Baltina, L. V. Spirikhin, G. A. Tolstikov

Journal:

Year:

2005

File:

PDF, 33 KB

2005

29

Synthesis and Pharmacological Activity of Betulin Esters, Betulinic Acids and Allobetulin.

O. B. Flekhter, N. I. Medvedeva, L. T. Karachurina, L. A. Baltina, F. Z. Galin, F. S. Zarudii, G. A. Tolstikov

Journal:

Year:

2006

File:

PDF, 18 KB

2006

30

Synthesis of 5-Hydroxy-1,3-benzoxathiol-2-one and 2-Amino-1,3-benzothiazol-6-ol Derivatives from Chrysenequinonecarboxylic Acid.

E. V. Tret'yakova, O. B. Flekhter, F. Z. Galin, E. E. Shul'ts, G. A. Tolstikov

Journal:

Year:

2006

File:

PDF, 22 KB

2006

31

Synthesis of squalamine analogues on the basis of lupane triterpenoids

Gulnara V. Giniyatullina, Oxana B. Flekhter, Genrikh A. Tolstikov

Journal:

Mendeleev Communications

Year:

2009

Language:

english

File:

PDF, 226 KB

english, 2009

32

Lupane triterpenes and derivatives with antiviral activity

L.A. Baltina, O.B. Flekhter, L.R. Nigmatullina, E.I. Boreko, N.I. Pavlova, S.N. Nikolaeva, O.V. Savinova, G.A. Tolstikov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 164 KB

english, 2003

33

Stereoselective synthesis of triterpene and steroid 2-deoxy-α-glycosides using iodonium dicollidine perchlorate

L. A. Baltina, O. B. Flekhter, E. V. Vasil'eva, G. A. Tolstikov

Journal:

Russian Chemical Bulletin

Year:

1997

Language:

english

File:

PDF, 383 KB

english, 1997

34

Stereoselective synthesis of triterpene 2-deoxy-α-d-lyxo-hexopyranosides

L. A. Baltina, O. B. Flekhter, E. V. Vasil'eva, G. A. Tolstikov

Journal:

Russian Chemical Bulletin

Year:

1997

Language:

english

File:

PDF, 366 KB

english, 1997

35

Glycosylation of betulin acetates with glycals

O. B. Flekhter, L. A. Baltina, L. V. Spirikhin, I. P. Baikova, G. A. Tolstikov

Journal:

Russian Chemical Bulletin

Year:

1998

Language:

english

File:

PDF, 354 KB

english, 1998

36

Direct stereospecific synthesis of triterpene and steroid 2-deoxy-α-glycosides

O. B. Flekhter, L. A. Baltina, G. A. Tolstikov

Journal:

Russian Chemical Bulletin

Year:

1997

Language:

english

File:

PDF, 334 KB

english, 1997

37

The synthesis and hepatoprotective activity of esters of the lupane group triterpenoids

O. B. Flekhter, L. T. Karachurina, V. V. Poroikov, L. P. Nigmatullina, L. A. Baltina, F. S. Zarudii, V. A. Davydova, L. V. Spirikhin, I. P. Baikova, F. Z. Galin, G. A. Tolstikov

Journal:

Russian Journal of Bioorganic Chemistry

Year:

2000

Language:

english

File:

PDF, 780 KB

english, 2000

38

Synthesis of 30-amino derivatives of 3,28-di-O-acetylbetulin

O. B. Flekhter, I. E. Smirnova, F. Z. Galin, G. V. Giniyatullina, E. V. Tret’yakova, G. A. Tolstikov

Journal:

Chemistry of Natural Compounds

Year:

2004

Language:

english

File:

PDF, 29 KB

english, 2004

39

Synthesis of the lupinine ester of betulonic acid

F. Z. Galin, V. G. Kartsev, O. B. Flekhter, G. V. Giniyatullina, G. A. Tolstikov

Journal:

Chemistry of Natural Compounds

Year:

2004

Language:

english

File:

PDF, 22 KB

english, 2004

40

Synthesis and Pharmacological Activity of 20-Keto-29-norlupane Derivatives

O. B. Flekhter, G. V. Giniyatullina, F. Z. Galin, N. Zh. Baschenko, N. S. Makara, F. S. Zarudii, E. I. Boreko, O. V. Savinova, N. I. Pavlova, Z. A. Starikova, G. A. Tolstikov

Journal:

Chemistry of Natural Compounds

Year:

2005

Language:

english

File:

PDF, 39 KB

english, 2005

41

Structure of the minor ozonolysis product of 19β,28-epoxy-A-neo-18α-olean-3(5)-ene

N. I. Medvedeva, O. B. Flekhter, A. Gzella, L. Zaprutko

Journal:

Chemistry of Natural Compounds

Year:

2006

Language:

english

File:

PDF, 37 KB

english, 2006

42

Synthesis of methyl esters of betulinic acid 2-deoxy-α-glycosides and 28-oxo-19,28-epoxyoleanane

O. B. Flekhter, N. I. Medvedeva, E. V. Tret’yakova, F. Z. Galin, G. A. Tolstikov

Journal:

Chemistry of Natural Compounds

Year:

2006

Language:

english

File:

PDF, 39 KB

english, 2006

43

Effective synthesis of methyl 3β-amino-3-deoxybetulinate

G. V. Giniyatullina, O. B. Flekhter, I. P. Baikova, Z. A. Starikova, G. A. Tolstikov

Journal:

Chemistry of Natural Compounds

Year:

2008

Language:

english

File:

PDF, 90 KB

english, 2008

44

Synthesis and Pharmacological Activity of Betulin, Betulinic Acid, and Allobetulin Esters

O. B. Flekhter, N. I. Medvedeva, L. T. Karachurina, L. A. Baltina, F. Z. Galin, F. S. Zarudii, G. A. Tolstikov

Journal:

Pharmaceutical Chemistry Journal

Year:

2005

Language:

english

File:

PDF, 78 KB

english, 2005

45

Synthesis of 19β,28-epoxy-23,24-dinor-A-neo-18α-olean-4-en-3-one from betulin

N. I. Medvedeva, O. B. Flekhter, O. S. Kukovinets, F. Z. Galin, G. A. Tolstikov, I. Baglin, C. Cavé

Journal:

Russian Chemical Bulletin

Year:

2007

Language:

english

File:

PDF, 280 KB

english, 2007

46

Synthesis of 5-Hydroxy-1,3-benzoxathiol-2-one and 2-Amino-1,3-benzothiazol-6-ol Derivatives from Chrysenequinonecarboxylic Acid

E. V. Tret’yakova, O. B. Flekhter, F. Z. Galin, E. E. Shul’ts, G. A. Tolstikov

Journal:

Russian Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 62 KB

english, 2005

47

Biological activity and pharmacological prospects of lupane terpenoids: II. Semisynthetic lupane derivatives

T. G. Tolstikova, I. V. Sorokina, G. A. Tolstikov, A. G. Tolstikov, O. B. Flekhter

Journal:

Russian Journal of Bioorganic Chemistry

Year:

2006

Language:

english

File:

PDF, 270 KB

english, 2006

48

Biological activity and pharmacological prospects of lupane terpenoids: I. natural lupane derivatives

T. G. Tolstikova, I. V. Sorokina, G. A. Tolstikov, A. G. Tolstikov, O. B. Flekhter

Journal:

Russian Journal of Bioorganic Chemistry

Year:

2006

Language:

english

File:

PDF, 217 KB

english, 2006

49

Synthesis and antiviral activity of lupane triterpenoids with modified cycle E

O. B. Flekhter, N. I. Medvedeva, O. S. Kukovinets, L. V. Spirikhin, E. G. Galkin, F. Z. Galin, D. G. Golovanov, N. I. Pavlova, O. V. Savinova, E. I. Boreko, G. A. Tolstikov

Journal:

Russian Journal of Bioorganic Chemistry

Year:

2007

Language:

english

File:

PDF, 267 KB

english, 2007

50

Betulonic amides modified at cycle a by amino acids: Synthesis and inhibition of flu A virus reproduction

O. B. Flekhter, N. I. Medvedeva, G. A. Tolstikov, O. V. Savinova, E. I. Boreko, F. M. Dolgushin

Journal:

Russian Journal of Bioorganic Chemistry

Year:

2009

Language:

english

File:

PDF, 277 KB

english, 2009

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